It depends on what kind of support you're looking for.

GO is our physician-formulated daily supplement for constipation, digestive regularity, and bloating. It's designed for consistent use with magnesium oxide and organic fennel seed.

Go Cleanse is for an occasional, more complete digestive reset when you're particularly backed up, such as after travel, a long weekend, or a change in routine. It is intended for occasional use only, up to 3 times per year.

Cleanse + GO combines the two: start with Go Cleanse for a digestive reset, then transition to GO for consistent daily regularity.

Go Colonoscopy Prep is specifically designed for bowel preparation before a colonoscopy and should be discussed with your healthcare provider before use.

Think of them by how and when they're used:

• GO: Daily support for constipation, regularity, and bloating.
• Go Cleanse: An occasional digestive cleanse when you need a more complete reset.
• Cleanse + GO: Reset first, then transition to daily regularity.
• Go Colonoscopy Prep: A dedicated bowel preparation protocol for colonoscopy.
  

Although Go Cleanse and Go Colonoscopy Prep share some components, they are intended and instructed for very different uses.

Different forms of magnesium behave differently in the body.

Magnesium oxide works primarily in the digestive tract and has an osmotic effect that helps soften stool and support regular bowel movements. It is included in clinical guidelines for chronic idiopathic constipation and is the form used in GO.

Magnesium citrate also works osmotically and is commonly used for more immediate or occasional constipation relief. It is the form included in Go Cleanse.

Magnesium glycinate is more readily absorbed and is generally chosen for systemic magnesium supplementation rather than its laxative effect.

The best form depends on why you're taking magnesium.

They work differently.

Osmotic laxatives, including magnesium oxide and magnesium citrate, help increase water in the intestine, making stool softer and easier to pass.

Stimulant laxatives, such as senna, directly stimulate intestinal contractions to help move stool through the bowel.

GO is stimulant-free and uses magnesium oxide for gentle, consistent daily support. Go Cleanse combines different approaches and is intended only for occasional use.

Magnesium oxide is included in AGA and ACG clinical guidelines as an evidence-based option for chronic idiopathic constipation. Unlike stimulant laxatives, it works osmotically rather than directly stimulating the bowel.

GO was formulated with magnesium oxide for consistent daily digestive support. As with any supplement, individual needs vary, particularly if you have kidney disease or take medications.

Many people experience a softer, easier-to-pass bowel movement within approximately 12–24 hours, although individual response varies.

That's one reason GO is taken in the evening: it is designed to provide gentle overnight digestive support for a more comfortable bowel movement the following day.

The Bristol Stool Chart is a simple clinical tool that categorizes stool into seven types based on shape and consistency.

Types 1 and 2 generally indicate harder stools associated with constipation, while Types 3 and 4 are typically considered more ideal. Types 6 and 7 represent increasingly loose or watery stools.

For GO, the goal isn't urgency or diarrhea. It's a soft, comfortable, easy-to-pass bowel movement.

Occasional constipation is common, but some symptoms deserve medical evaluation.

Talk with your healthcare provider if constipation is new or persistent, significantly different from your usual bowel habits, or accompanied by symptoms such as blood in the stool, unexplained weight loss, significant abdominal pain, vomiting, fever, or an inability to pass stool or gas.

Persistent constipation despite changes in diet, hydration, movement, or over-the-counter support is also worth discussing with your healthcare provider.