





When to use GO:
GO is designed for gentle, consistent daily digestive support and is commonly used for:
- Chronic constipation
- Occasional constipation
- IBS-C support*
- GLP-1–associated constipation*
- Constipation related to medications*
- Travel constipation
- Perimenopause-related constipation
- Bloating after meals
- Daily digestive regularity
- Healthy bowel movements
What's inside:
Active ingredients (per 1-capsule):
- 517 mg Magnesium Oxide (yielding 300 mg Magnesium)
- 150 mg Organic Fennel Seed (Foeniculum vulgare)
Serving size: 2 vegetarian capsules
View Supplement Facts
Supply: 60 capsules per bottle
Free from: Emulcifiers, artificial colors, preservatives, gluten, dairy, soy, and GMOs.
Formulated for: Daily support for constipation and bloating. Non-habit forming and stimulant-free.How to use:
- Start: Take 1 capsule in the evening with a full glass of water.
- Adjust: If needed, increase by 1 capsule every night (up to 3 capsules) to reach a Bristol Stool Scale Type 4 (smooth, soft, easy to pass). Most patients required 2 capsules for best results.
- Consistency: Use nightly and pair with fiber-rich foods, hydration, gentle movement, and a regular toilet routine for best results.
- Timing tips: Many people prefer taking Go 30–60 minutes before bed. If you’re sensitive, start on a weekend to learn your best dose.
Why it works:
- Hydrates the stool (magnesium oxide): Mostly unabsorbed in the gut, magnesium oxide draws water into the stool to soften its texture and support comfortable, regular bowel movements—without the harshness of stimulant laxatives.
- Relaxes intestinal muscles (organic fennel seed): Fennel’s key compound, anethole, has a gentle spasmolytic effect that can ease gas, cramping, and bloating while supporting balanced motility.
What you'll feel:
- Softer, easier-to-pass stools
- Less cramping and bloating discomfort
- A gentler experience compared to stimulant laxatives
Who it's for:
- Adults seeking gentle, clean support for constipation and bloating.
- People who want a stimulant-free, additive-free option.
Who should ask a clinician before using:
- If you have kidney disease, inflammatory bowel disease, are on magnesium-containing medications, have a history of bowel obstruction, severe abdominal pain, nausea/vomiting, or a sudden change in bowel habits lasting >2 weeks.
- Pregnant or nursing: please consult your healthcare provider first.
- Children: use only under medical guidance.
Key Points
- Two-pronged relief: Magnesium oxide hydrates stool; organic fennel eases intestinal spasms.
- Physician-formulated: Built on clinical insight for gentle, effective relief.
- Clean label: No fillers, additives, or harsh stimulants—just naturally derived, evidence-informed ingredients.
- Non-habit forming.
What to expect (timeline):
- Days 1–3: Find your dose (1–3 caps); notice softer stools.
- Week 1: More regularity and less straining.
- Week 2+: Steadier rhythm; adjust dose as life/routine changes.
FAQ
Why magnesium oxide for constipation?
Magnesium oxide is an evidence-based osmotic laxative included in AGA and ACG clinical guidelines for chronic idiopathic constipation. It works primarily in the digestive tract, helping draw water into the intestine to soften stool and support easier, more regular bowel movements without stimulant ingredients.
That evidence is one of the reasons we chose magnesium oxide as the foundation of GO.
Can GO be used for chronic or occasional constipation?
Yes. GO is designed for daily digestive support for both occasional constipation and ongoing regularity. Its combination of magnesium oxide and organic fennel seed supports softer, more regular bowel movements while helping ease bloating and digestive discomfort.
If constipation is new, severe, worsening, or accompanied by concerning symptoms, speak with your healthcare provider.
Does GO support bowel motility?
GO supports healthy bowel function and transit primarily through magnesium oxide's osmotic action. Clinical studies of magnesium oxide for chronic constipation have evaluated improvements in bowel movements, stool consistency, constipation symptoms, and colonic transit.
GO is not a traditional prokinetic or stimulant laxative.
Can GO help with GLP-1–associated constipation?
GLP-1 medications such as Ozempic, Wegovy, Mounjaro, and Zepbound can slow gastrointestinal motility and contribute to constipation and bloating. GO provides stimulant-free daily digestive support with magnesium oxide for softer, more regular bowel movements and organic fennel seed to help ease bloating.
Talk with your healthcare provider about persistent or severe constipation or before adding supplements to your medication regimen.
Can GO be used for constipation related to other medications?
Some medications can contribute to constipation by slowing intestinal movement, changing stool consistency, or affecting hydration. GO provides daily digestive support for regular bowel movements, but new or persistent medication-related constipation should be discussed with your healthcare provider.
Can GO help with travel constipation?
Yes. Travel constipation is common when changes in routine, hydration, diet, or sleep throw off your usual bowel habits. GO is taken in the evening and typically works overnight, making it an easy option to support a more regular bowel movement the next morning while traveling.
If constipation tends to be something you experience specifically with travel, GO can be used when you need that extra support.
Can GO support constipation and bloating during perimenopause and menopause?
Hormonal changes during perimenopause and menopause can be accompanied by changes in gastrointestinal function, bowel habits, and bloating. Some women notice new or worsening constipation as they move through this transition.
GO supports daily digestive regularity with magnesium oxide, while organic fennel seed provides additional digestive support for bloating and discomfort. For women experiencing constipation during perimenopause or menopause, GO offers gentle, stimulant-free support for more regular bowel movements.
What about IBS-C?
People with IBS-C commonly experience constipation, bloating, and abdominal discomfort. GO contains magnesium oxide to support regular bowel movements and organic fennel seed to help ease bloating and digestive discomfort.
GO is designed to support constipation and bloating rather than treat IBS itself. Individual needs and tolerance can vary.
What about SIBO, IMO, or ISO?
SIBO (small intestinal bacterial overgrowth), IMO (intestinal methanogen overgrowth), and ISO (intestinal sulfide overproduction) are distinct patterns of microbial overgrowth that can be associated with bloating, gas, abdominal discomfort, and changes in bowel habits.
Intestinal motility matters. Slower transit can contribute to an environment in which microbial overgrowth may occur, while methane production in IMO has itself been associated with slower intestinal transit and constipation. Supporting healthy bowel function and addressing constipation can therefore be an important part of the overall digestive picture, particularly in people with IMO.
GO does not treat or eradicate SIBO, IMO, or ISO. Magnesium oxide works osmotically to soften stool and support regular bowel movements and healthy transit, while organic fennel seed provides additional support for bloating and digestive discomfort.
If you have diagnosed or suspected SIBO, IMO, or ISO, treatment of the underlying overgrowth and any contributing motility disorder should be individualized with your healthcare provider.
Could fennel support intestinal barrier function or “leaky gut”?
“Leaky gut” is a common term for increased intestinal permeability, when the intestinal barrier becomes more permeable than normal.
There is interesting emerging research on fennel seed and intestinal barrier health. In preclinical research, fennel seed extract demonstrated protective effects on the intestinal barrier, including preservation of barrier integrity and increased expression of genes associated with tight junctions, the structures that help regulate what passes through the intestinal lining.
GO contains organic fennel seed as part of its simple two-ingredient formula. While GO is designed primarily to support constipation, regularity, and bloating, the emerging research around fennel and intestinal barrier function is another interesting potential digestive benefit of this traditional botanical.
Can GO be used while following a low-FODMAP diet?
GO contains just two active ingredients: magnesium oxide and organic fennel seed, without added fermentable fibers, prebiotics, or sugar alcohols. Its simple formula can make it easy to incorporate into a low-FODMAP digestive routine, although individual tolerance varies.
Is GO a stimulant laxative?
No. GO is stimulant-free. Magnesium oxide works osmotically by helping retain water in the intestine to soften stool and support regular bowel movements rather than directly stimulating intestinal contractions.
Is GO habit-forming?
No. GO is stimulant-free, non-habit forming, and designed for consistent daily use. Magnesium oxide does not work by stimulating the bowel to contract.
Can I take GO every night?
Yes. GO is designed for consistent daily use. Start with 1 capsule in the evening and gradually adjust to the lowest effective dose, up to 3 capsules, with the goal of a soft, easy-to-pass bowel movement.
If constipation persists or worsens despite use, speak with your healthcare provider.
How quickly does GO work?
Many people notice softer, easier-to-pass bowel movements within 12–24 hours. Individual response varies, so start low and gradually adjust your dose while maintaining adequate hydration and fiber intake.
Will GO cause urgency or cramping?
GO is stimulant-free and designed for gentle, consistent digestive support rather than urgency. Individual responses vary. If stools become too loose, reduce your dose.
Does GO help with bloating?
GO approaches regularity and bloating together. Magnesium oxide supports softer, more regular bowel movements, while organic fennel seed provides additional digestive support for bloating and discomfort.
Can I take another type of magnesium, like magnesium glycinate for sleep, with GO?
Yes. Different forms of magnesium can serve different purposes. Magnesium glycinate is more readily absorbed and is often used for systemic magnesium supplementation, while the magnesium oxide in GO works primarily in the digestive tract, where its osmotic effect helps support softer, more regular bowel movements.
Because both contribute to your total magnesium intake, discuss combining magnesium supplements with your healthcare provider, particularly if you take medications or have kidney disease.
Can I take GO with fiber or probiotics?
Yes. GO can be incorporated into a digestive routine that includes fiber-rich foods, adequate hydration, movement, and probiotics if you use them.
Can I take GO during pregnancy or while breastfeeding?
Please consult your healthcare provider before using GO during pregnancy or while breastfeeding.
Is GO gluten-free, dairy-free, and soy-free?
Yes. GO is vegetarian, gluten-free, dairy-free, soy-free, and non-GMO.
Can GO capsules be opened?
GO is designed to be taken as an intact capsule. We do not recommend opening the capsules or mixing the contents into water, beverages, or food.
Is GO third-party tested?
Yes. GO undergoes independent third-party testing to evaluate the quality of the finished product, including magnesium content, elemental analysis, microbial quality, and finished-product testing.
Could GO help support healthy pelvic floor function?
Yes. Constipation, hard stools, and repeated straining can place added stress on the pelvic floor and may contribute to pelvic floor tension and difficulty with bowel movements. In turn, pelvic floor dysfunction can make constipation worse, creating a frustrating cycle.
By helping soften stool and support easier, more regular bowel movements, the magnesium oxide in GO may help reduce the need to strain and support healthier bowel habits. Magnesium also plays an important role in normal muscle and neuromuscular function, while organic fennel seed has traditionally been used for digestive comfort and has demonstrated antispasmodic activity in preclinical research.
Supporting softer stools, regular bowel movements, and less straining can be an important part of supporting healthy pelvic floor function and helping break the constipation-straining cycle.
Is GO low-histamine and MCAS-friendly?
GO contains just two active ingredients: magnesium oxide and organic fennel seed. Magnesium oxide is an inorganic mineral salt that does not itself contain histamine, making it generally compatible with a low-histamine approach.
There is also interesting preclinical research suggesting that magnesium may help modulate mast cell activity, including mast cell degranulation and histamine release. Fennel and fennel-derived compounds have also demonstrated antihistaminic activity in laboratory and animal studies.
For people with MCAS or histamine intolerance, individual sensitivities and triggers can vary significantly. We recommend reviewing any new supplement with your healthcare provider and considering your own known triggers.
Could fennel support digestive health in Candida overgrowth or SIFO?
SIFO, or small intestinal fungal overgrowth, occurs when fungi, often Candida species, are present in excessive amounts in the small intestine and may contribute to bloating, gas, abdominal discomfort, and changes in bowel habits.
Fennel has traditionally been used for digestive support, and laboratory research has found that certain fennel-derived compounds and extracts demonstrate antifungal activity against Candida species. Organic fennel seed in GO also provides digestive support for bloating and discomfort, which may be particularly relevant when these symptoms are part of the picture.
GO is not intended to treat Candida overgrowth or SIFO. If you have diagnosed or suspected SIFO, we recommend incorporating digestive support into an individualized plan with your healthcare provider.
Safety & disclaimers:
Warning: Do not use it if you have kidney disease, inflammatory bowel disease, known magnesium allergy, bowel obstruction, severe abdominal pain, unexplained rectal bleeding, or a sudden change in bowel habits lasting more than 2 weeks. Stop use and consult a healthcare professional if you experience persistent diarrhea, worsening symptoms, or allergic reaction. If pregnant, nursing, taking medication, or have a medical condition, consult your physician before use.Drug interactions: Magnesium may interact with certain medications (e.g., some antibiotics and thyroid medications). Take medications and magnesium-containing products at separate times as advised by your clinician.
FDA statement: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

