Go: Natural, Daily Relief for GLP-1-Induced Constipation

GLP-1 medications slow your entire gut through three distinct mechanisms. Go was formulated to address exactly this — with two targeted, non-stimulant ingredients that work with your body, not against it.

  • Physician-formulated

  • Non-habit forming

  • Gentle for daily use

  • Non-GMO

  • Vegetarian

  • Allergen free

  • cGMP certified

  • Third Party Tested

Why Most Laxatives Don’t Work Well for GLP-1 Patients

Choosing Constipation Support While Taking a GLP-1

Not all constipation treatments work the same way. Understanding the difference can help you choose an approach that fits your symptoms and your routine.

Stimulant laxatives, such as senna and bisacodyl, stimulate intestinal contractions to help move stool through the bowel. They can be useful for short-term or rescue relief, but may be more likely to cause urgency or cramping for some people.

Osmotic laxatives work differently. They help increase water in the intestine, softening stool and making it easier to pass. Magnesium oxide is an osmotic laxative included in AGA and ACG clinical guidelines for chronic idiopathic constipation.

GO takes an osmotic, stimulant-free approach with magnesium oxide for bowel regularity, paired with organic fennel seed for additional digestive support for bloating and discomfort.

How Go Works

Two ingredients. Two Complementary Roles.

  • Magnesium oxide — 300 mg elemental magnesium

    Magnesium oxide works primarily in the digestive tract, where its osmotic effect helps increase water in the intestine, softening stool and making bowel movements easier to pass. Magnesium oxide is supported by clinical literature and included in AGA and ACG guidelines for chronic idiopathic constipation.

  • Organic fennel seed — 150 mg (Foeniculum vulgare)

    Fennel has a long history of use for digestive comfort. Its naturally occurring compounds, including anethole, have been studied for their effects on gastrointestinal smooth muscle and digestive symptoms. In GO, organic fennel seed provides additional support for bloating and digestive discomfort.

The Key Insight

GLP-1 medications can slow gastrointestinal transit, contributing to harder stools, less frequent bowel movements, straining, and bloating.

Magnesium oxide addresses an important part of that picture by helping retain water in the intestine, supporting softer, easier-to-pass stools without stimulant ingredients. Organic fennel seed provides complementary digestive support for bloating and discomfort.

Together, they offer a simple, two-ingredient approach to daily digestive support while taking a GLP-1.

What to Expect

  • Start Low

    Begin with 1 capsule in the evening with a full glass of water. Many people notice softer, easier-to-pass stools within 12–24 hours.

  • Find Your Dose

    If needed, gradually increase by 1 capsule each evening, up to 3 capsules, until you reach a soft, comfortable, easy-to-pass bowel movement.

  • Stay Consistent

    Once you find the dose that works for you, GO is designed for consistent daily support. Your needs may change with diet, hydration, travel, or changes in your GLP-1 dose.

Testimonials

“I was stuck on senna and needing higher doses with time — so frustrated with my dependence. After starting Go I was able to wean off senna completely. Two Go every night has been a game changer. Never felt better!”

Rob C., Verified Purchaser

“I have gone every day for the past two weeks, which hasn’t happened in YEARS!”

Verified Purchaser

“Since perimenopause, my bowel movements totally changed and I felt 9 months pregnant with bloating. Taking Go daily has changed my symptoms completely — letting me live my life and feel amazing!”

Leni I., Verified Purchaser

Frequently Asked Questions

  • GLP-1 medications slow gastrointestinal motility and can delay the movement of food and stool through the digestive tract. As stool remains in the colon longer, more water can be absorbed, contributing to harder stools, less frequent bowel movements, straining, and bloating.

  • Constipation can occur with GLP-1 and related medications including semaglutide (Ozempic and Wegovy) and tirzepatide (Mounjaro and Zepbound). Individual symptoms vary and may change when starting treatment or adjusting medication doses.

  • GO is designed to provide gentle, stimulant-free digestive support for constipation and bloating, including when these symptoms occur while taking a GLP-1 medication.

    Because individual medical histories and medication regimens vary, discuss adding any supplement with your healthcare provider, particularly if constipation is persistent or severe.

  • For some people, gastrointestinal side effects improve as the body adjusts to a GLP-1 medication. For others, constipation can persist or recur, particularly after dose increases.

    Maintaining hydration, adequate fiber intake, regular movement, and a consistent bowel routine can help support regularity while taking a GLP-1.

  • Magnesium oxide is an osmotic laxative supported by clinical literature and GI guidelines for chronic constipation. It works primarily in the digestive tract, helping increase water in the stool so bowel movements are softer and easier to pass.

    GO combines magnesium oxide with organic fennel seed to provide additional digestive support for bloating and discomfort.

  • Hydration, adequate dietary fiber, regular movement, and maintaining a consistent bathroom routine can all support bowel regularity. Because GLP-1 medications can reduce appetite and overall food intake, it's important to pay attention to fluid and fiber intake even when you're eating less.

    If constipation is severe or persistent, or accompanied by significant abdominal pain, vomiting, or an inability to pass stool or gas, contact your healthcare provider.

  • GO is designed for consistent daily use. Magnesium oxide works osmotically rather than as a stimulant laxative and is included in GI clinical guidelines as an evidence-based option for chronic constipation.

    Individual needs vary, so persistent or changing constipation should be discussed with your healthcare provider.

  • Yes. GO can be incorporated into a digestive routine that includes dietary fiber, fiber supplements, adequate hydration, movement, and probiotics if you use them.

    If increasing fiber significantly worsens bloating or discomfort, discuss your symptoms with your healthcare provider rather than continuing to add more fiber.

  • No. GO is stimulant-free and non-habit forming. Magnesium oxide works osmotically by helping retain water in the intestine to soften stool and support regular bowel movements rather than directly stimulating intestinal contractions.

Ready to feel regular again?

Physician-formulated. Clean label. Designed for daily use.

  • One-time purchase - $30

    60 capsules · Free shipping

  • Subscribe & save - $26/mo

    Best for GLP-1 patients · Cancel anytime after 3 months