The Science Behind Go Cleanse

The Go Cleanse natural gut cleanse works by harnessing two proven mechanisms for supporting healthy bowel movements:

Magnesium (osmotic effect)

Magnesium citrate acts as an osmotic agent, drawing water into the intestinal lumen. By increasing water in the gut, stool becomes softer and larger, which gently stimulates peristalsis—the natural muscle contractions that move waste along the digestive tract. This typically results in smoother, easier, and faster bowel movements. Because this process relies on water and can affect electrolyte levels, staying well hydrated and replenishing electrolytes—like those included in the Go Cleanse kit—is important to help you feel balanced and comfortable.

Senna (stimulant effect)

Senna’s active plant compounds, called sennosides, are converted by beneficial gut bacteria into substances that stimulate the colon. This leads to increased secretion of water and gentle activation of colon muscles, helping move intestinal contents toward elimination.

A gentle, effective team

Magnesium softens and hydrates stool, while senna encourages the colon to contract. Together, these ingredients help restore natural regularity, making elimination more comfortable and supporting the body’s natural rhythm—all in a way that is gentle and well tolerated.

Evidence for Resetting Gut Motility

Clinical research supports the role of bowel cleansing for improving colonic transit in people with constipation. In one study, average colonic transit time decreased from about 70 hours before cleansing to 48 hours after, with improvement seen across all segments of the colon. People with especially slow motility—often called “slow transit constipation”—showed markedly improved bowel patterns following a cleanse. 

This research highlights an important principle: retained stool or fecal impaction can slow transit significantly. By clearing this backlog, a cleanse helps restore more natural movement and rhythm to the digestive tract. 

Everyday Applications

Beyond chronic constipation, occasional cleansing may reset gut function if you’ve missed several bowel movements due to life disruptions like travel, stress, or changes in routine. By supporting motility, hydration, and regularity, Go Cleanse helps get digestion back on track and working as it should.

  • After Your Cleanse

    Cleansing helps clear out retained waste and may create an opportunity for your gut microbiome—the community of good bacteria—to rebalance. How effectively your microbiome rebounds depends on what you eat afterwards. For best results, take advantage of this “fresh start” by:

    • Drinking plenty of fluids to support hydration and electrolyte balance.
    • Avoiding processed foods that encourage less-beneficial bacteria.
    • Increasing prebiotic fiber intake (about 40g/day as tolerated).
    • Eating a variety of plants (aim for 30+ each week).
    • Adding daily servings of fermented foods like kimchi, sauerkraut, kefir, or miso soup.

    Nourishing your gut with these choices after cleansing helps friendly microbes thrive, which supports not only digestion, but also immune and metabolic health. 

  • How Often Should a Cleanse Be Used?

    For most healthy adults, an occasional cleanse can support gut health—especially after periods of stress, travel, or missed bowel movements. Experts recommend using a cleanse no more than four times per year—once per season—for ongoing wellness. This approach supports regularity without risking dependency on laxatives or interfering with natural digestive rhythms. 

    Reference: https://pubmed.ncbi.nlm.nih.gov/11874554/